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Abstract

Introduction and purpose

Severe Acute Respiratory Syndrome Coronavirus-2 requires angiotensin-converting enzyme 2 to enter the cell. In our study, we aimed to investigate the role of angiotensin-converting enzyme 2 and Angiotensin II plasma levels on prognosis and mortality in patients with isolated hypertension, patients with chronic diseases in addition to hypertension, and patients with COVID-19 without comorbidities, in accordance with the use of renin-angiotensin-aldosterone system inhibitor.

Material and Method

In the study, patients diagnosed with COVID-19 were divided into three groups. Angiotensin II and angiotensin-converting enzyme 2 levels were compared by comorbidities, antihypertensive drugs used, intensive care hospitalization, and termination of patients. The relationship between Angiotensin II and angiotensin-converting enzyme 2 levels and service and intensive care times was investigated.